Dr. Kranias’ research focusses on molecular mechanisms regulating cardiac function and survival. She received her Ph.D. degree from Northwestern University and pursued postdoctoral training at Northwestern University Medical School. In 1978, she started her faculty career at the University of Cincinnati Medical Center.
The Kranias’ research program has provided fundamental insights into the regulatory mechanisms and signaling pathways underlying calcium homeostasis in cardiac physiology and pathophysiology with special emphasis in heart failure. Dr. Kranias has extended her basic research findings to the clinical arena and has elucidated the functional significance of Ca-handling in the deteriorated function of human failing hearts.
She has also identified human mutations in calcium cycling genes and showed that these may predispose to arrhythmias and heart failure. The overall goal of her research program is to build a comprehensive understanding on the role of calcium cycling in cardiac contractility and cell survival.
Dr. Kranias has been invited to organize, chair and speak at numerous National and International meetings. She has also been a dedicated mentor of over 70 Ph.D. students and post-doctoral fellows. Dr. Kranias has received many National and International awards and honors. She has been named an AHA Distinguished Scientist and has been elected as a corresponding member of the Academy of Athens.
Dr. Kranias has also served on the Council of the Biophysical Society, the Council of the ISHR (International and NA), the AHA Research Committee, and as Associate Editor or Editorial Board member of several journals as well as reviewer on numerous panels and committees.
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